B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells <i>in vitro</i>

Abstract excerpt

The activation of T cells is now thought to require at least two distinct signals. One signal is delivered through the interaction of the antigen-specific T cell receptor with major histocompatibility complex (MHC) molecules and peptide, while the other is received from interactions with less precisely defined accessory or costimulatory molecules. In the absence of this second costimulatory signal, some T cells...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Adhesion Molecules Research
• Share to Immunotherapy and Immune Responses
• Share to T-cell and B-cell Immunology