Article
Cell type- and stage-specific expression of the CD20/B1 antigen correlates with the activity of a diverged octamer DNA motif present in its promoter.
The Journal of biological chemistry - 15 Mar 1993
Thévenin C, Lucas B P, Kozlow E J, Kehrl J H
Abstract excerpt
The CD20(B1) gene encodes a B cell-specific protein involved in the regulation of human B cell proliferation and differentiation. Studies with 5' deletion CD20 promoter-CAT constructs have previously revealed two regions of the promoter between bases -186 and -280 and between bases -280 and -454...
Topics
- Antigens, CD
- Antigens, CD20
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Base Sequence
- Binding Sites
- Cell Line
- DNA
- DNA Mutational Analysis
- DNA-Binding Proteins
- HeLa Cells
- Host Cell Factor C1
- Humans
- Molecular Sequence Data
- Mutation
- Octamer Transcription Factor-1
- Octamer Transcription Factor-2
- Promoter Regions, Genetic