Article
CD20: a gene in search of a function.
Seminars in oncology - 1 Dec 2000
Riley J K, Sliwkowski M X
Abstract excerpt
CD20 is a signature B-cell differentiation antigen. The function of CD20 is unknown, although it is thought to be involved in B-cell activation, regulation of B-cell growth, and transmembrane calcium flux. This review covers several topics important for understanding CD20 biology. These topics include the expression pattern and transcriptional regulation of the CD20 gene, the structure of the protein and its...
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