Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells.

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Article

Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells.

Blood - 1 Mar 1993

Moreau I, Duvert V, Banchereau J, Saeland S

Abstract excerpt

Growth of human B-cell precursors (BCP) was achieved by plating fetal CD10+ surface-mu (s mu)- cells in liquid medium onto bone marrow-derived fibroblastic stromal cell layers deprived of hematopoietic cells. Proliferation of the fetal BCP was strongly potentiated by the addition of interleukin-7...

Topics

Antigens, CD
Antigens, CD20
Antigens, Differentiation, B-Lymphocyte
B-Lymphocytes
Bone Marrow Cells
Cell Count
Cell Division
Cells, Cultured
Female
Fetus
Hematopoietic Stem Cells
Humans
Immunoglobulin M
Neprilysin
Phenotype
Pregnancy
Receptors, Antigen, B-Cell
Stromal Cells

Source

Open in PubMed

Identifiers

PMID: 7680240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7680240-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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