Article
Enrichment of primary lymphocyte-supporting stromal cells and characterization of associated B lymphocyte progenitors.
European journal of immunology - 1 May 1992
Funk P E, Witte P L
Abstract excerpt
Studies of Whitlock/Witte long-term bone marrow cultures have revealed the necessity of two cell types for B lymphopoiesis, a stem cell and the stromal cell. While a number of stromal cell lines exist they have been found to be heterogeneous with respect to cell surface marker expression and growth factor production. Separation and analysis of fresh bone marrow stromal cells is, therefore, necessary to understand...
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