Article
Expression of an inaccessible P1.7 subtype epitope on meningococcal class 1 proteins.
Journal of medical microbiology - 1 Jan 1993
Wedege E, Dalseg R, Caugant D A, Poolman J T, Frøholm L O
Abstract excerpt
Dot-blot analysis of whole-cell suspensions of meningococci showed that 81% of B:15:P1.16 strains from patients reacted with a monoclonal antibody (MAb) against subtype P1.7. The remaining strains, which did not react on dot-blots or in ELISA, demonstrated the P1.7 subtype epitope on immunoblots after denaturation of the cells with sodium dodecyl sulphate. The monomeric class 1 proteins of the two P1.16 subtype...
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