Article
Point mutation in meningococcal por A gene associated with increased endemic disease.
Lancet (London, England) - 2 Mar 1991
McGuinness B T, Clarke I N, Lambden P R, Barlow A K, Poolman J T, Jones D M, Heckels J E
Abstract excerpt
The por A gene, which encodes expression of meningococcal class 1 outer membrane protein, responsible for antigenic subtype specificity, has been cloned and sequenced in an isolate of Neisseria meningitidis (B:15:P1.7,16) from a patient in the Gloucester area with meningococcal meningitis. Compar...
Topics
- Antibodies, Monoclonal
- Bacterial Outer Membrane Proteins
- Base Sequence
- DNA, Bacterial
- England
- Epitopes
- Humans
- Meningitis, Meningococcal
- Molecular Sequence Data
- Mutation
- Neisseria meningitidis
- Polymerase Chain Reaction