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Article

Identification of meningococcal serosubtypes by polymerase chain reaction.

Journal of clinical microbiology - 1 Nov 1992

Maiden M C, Bygraves J A, McCarvil J, Feavers I M

Abstract excerpt

The polymerase chain reaction was used as the basis of a novel typing method for Neisseria meningitidis. Southern hybridization experiments demonstrated that it was possible to identify genes encoding different serological variants of the meningococcal class 1 outer membrane protein by probing with polymerase chain reaction products corresponding to known epitopes. A set of 14 defined variable regions was...

Topics

Bacterial Outer Membrane Proteins
Bacterial Typing Techniques
Base Sequence
DNA, Bacterial
Genes, Bacterial
Genetic Variation
Humans
Molecular Sequence Data
Neisseria meningitidis
Polymerase Chain Reaction
Serotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1452652
DOI: 10.1128/jcm.30.11.2835-2841.1992
PMCID: PMC270538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1452652-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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