Article
Identification of meningococcal serosubtypes by polymerase chain reaction.
Journal of clinical microbiology - 1 Nov 1992
Maiden M C, Bygraves J A, McCarvil J, Feavers I M
Abstract excerpt
The polymerase chain reaction was used as the basis of a novel typing method for Neisseria meningitidis. Southern hybridization experiments demonstrated that it was possible to identify genes encoding different serological variants of the meningococcal class 1 outer membrane protein by probing with polymerase chain reaction products corresponding to known epitopes. A set of 14 defined variable regions was...
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