Article
A new variant of serosubtype P1.16 in Neisseria meningitidis from Norway, associated with increased resistance to bactericidal antibodies induced by a serogroup B outer membrane protein vaccine.
Microbial pathogenesis - 1 Sept 1993
Rosenqvist E, Høiby E A, Wedege E, Caugant D A, Frøholm L O, McGuinness B T, Brooks J, Lambden P R, Heckels J E
Abstract excerpt
Based on differences in reaction pattern with monoclonal antibodies against the P1.16 epitope, a new variant of the class 1 protein in Neisseria meningitidis serogroup B was identified in Norway. A single amino acid deletion was revealed when the part of the gene region encoding the second variable region of the protein was sequenced. This new variant was designated P1.16c. About 5% of the B:15:P1.7,16 strains in...
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