Article
A new variant of serosubtype P1.16 in Neisseria meningitidis from Norway, associated with increased resistance to bactericidal antibodies induced by a serogroup B outer membrane protein vaccine.
Microbial pathogenesis - 1 Sept 1993
Rosenqvist E, Høiby E A, Wedege E, Caugant D A, Frøholm L O, McGuinness B T, Brooks J, Lambden P R, Heckels J E
Abstract excerpt
Based on differences in reaction pattern with monoclonal antibodies against the P1.16 epitope, a new variant of the class 1 protein in Neisseria meningitidis serogroup B was identified in Norway. A single amino acid deletion was revealed when the part of the gene region encoding the second variab...
Topics
- Amino Acid Sequence
- Antibodies, Bacterial
- Antibodies, Monoclonal
- Antigenic Variation
- Bacterial Outer Membrane Proteins
- Bacterial Vaccines
- England
- Epitopes
- Genotype
- Humans
- Meningococcal Infections
- Molecular Sequence Data
- Neisseria meningitidis