Focal microsatellite mutations in relatives with prostatic adenocarcinoma.

Article

Focal microsatellite mutations in relatives with prostatic adenocarcinoma.

Anticancer research - 1 Jan 2000

Wille A H, Terrell R B, Cheville J C, Sheffield V C, Cohen M B

Abstract excerpt

Instability of short tandem repeat sequences, microsatellite instability (MI), has been reported to play an important role in the tumorigenesis of various adenocarcinomas, including prostatic adenocarcinoma. Although prostate cancer is not widely recognized as a heriditary cancer, familial cluste...

Topics

Adenocarcinoma
Aged
Family
Genetic Markers
Humans
Male
Microsatellite Repeats
Mutation
Prostatic Neoplasms

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