Article
Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes.
The Journal of biological chemistry - 4 Jun 2004
Zapata David A, Schamel Wolfgang W A, Torres Pilar S, Alarcón Balbino, Rossi Nineth E, Navarro María N, Toribio María L, Regueiro José R
Abstract excerpt
We have reported the existence of biochemical and conformational differences in the alphabeta T cell receptor (TCR) complex between CD4(+) and CD8(+) CD3gamma-deficient (gamma(-)) mature T cells. In the present study, we have furthered our understanding and extended the observations to primary T lymphocytes from normal (gamma(+)) individuals. Surface TCR.CD3 components from CD4(+) gamma(-) T cells, other than...
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