Article
T-cell receptor gamma/delta: comparison of gene configurations and function between humans and chimpanzees.
Immunogenetics - 1 Jan 1992
Sturm E, Bontrop R E, Vreugdenhil R J, Otting N, Bolhuis R L
Abstract excerpt
The human and chimpanzee T-cell receptor gamma-delta (TCR gamma delta) bearing cells represent a minor subset (3-8%) of T lymphocytes. In the periphery, the TCR gamma delta population has a restricted combinatorial repertoire. The TCRD-V1 and -V2 gene products are expressed in a mutually exclusive fashion, whereas, the TCRD-V2 and the TCRG-V9 encoded proteins show, in general, a coordinated expression....
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Biological Evolution
- Blotting, Southern
- Burkitt Lymphoma
- Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
