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Article

Amelioration of the behavioral phenotype in weaver mutant mice through bilateral intrastriatal grafting of fetal dopamine cells.

Experimental brain research - 1 Jan 1995

Triarhou L C, Norton J, Hingtgen J N

Abstract excerpt

Weaver mutant mice lose more than two-thirds of their nigral dopamine neurons. Behaviorally, weaver homozygotes display tremor, gait instability, and toppling over to the sides after a few steps. The recovery of functional responses was determined in a battery of behavioral tests in weaver mutants after bilateral transplantation of mesencephalic cell suspensions (prepared from wild-type mice) to the striatum....

Topics

Animals
Behavior, Animal
Brain Tissue Transplantation
Corpus Striatum
Dopamine
Immunohistochemistry
Locomotion
Mice
Mice, Mutant Strains
Phenotype
Prosencephalon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 7672013
DOI: 10.1007/BF00242005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7672013-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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