Transplantation of human striatal tissue into a rodent model of Huntington's disease: phenotypic expression of transplanted neurons and host-to-graft innervation.

doi:10.1016/0361-9230(95)02029-2

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Article

Transplantation of human striatal tissue into a rodent model of Huntington's disease: phenotypic expression of transplanted neurons and host-to-graft innervation.

Brain research bulletin - 1 Jan 1996

Pundt L L, Kondoh T, Conrad J A, Low W C

Abstract excerpt

The present study was undertaken to investigate the phenotypic expression and integration of human striatal neurons transplanted into an animal model of Huntington's disease. Sprague-Dawley rats were anesthetized and subjected to quinolinic acid lesions of the left striatum. Three human fetal cad...

Topics

Acetylcholinesterase
Animals
Brain Tissue Transplantation
Cell Survival
Cell Transplantation
Glial Fibrillary Acidic Protein
Humans
Huntington Disease
Immunohistochemistry
Male
NADPH Dehydrogenase
Neostriatum
Neurons
Phenotype
Rats
Rats, Sprague-Dawley
Tyrosine 3-Monooxygenase

Source

Open in PubMed

Identifiers

PMID: 8846104
DOI: 10.1016/0361-9230(95)02029-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8846104-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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