Article
Association of angiotensin-converting enzyme activity and polymorphism with echocardiographic measures in familial and nonfamilial hypertrophic cardiomyopathy.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Aug 2009
Buck P C, Fernandes F, Arteaga E, Matsumoto A Y, Araujo A Q, Oliveira E M, Ianni B M, Ramires F J A, Krieger J E, Mady C
Abstract excerpt
Angiotensin-converting enzyme (ACE) activity and polymorphism contribute significantly to the prognosis of patients with cardiomyopathy. The aim of this study was to determine the activity and type of ACE polymorphism in patients with familial and nonfamilial hypertrophic cardiomyopathy (HCM) and to correlate these with echocardiographic measurements (echo-Doppler). We studied 136 patients (76 males) with HCM (69...
Topics
- Adult
- Cardiomyopathy, Hypertrophic
- Cardiomyopathy, Hypertrophic, Familial
- Echocardiography, Doppler
- Female
- Genotype
- Humans
- Hypertrophy, Left Ventricular
- Male
- Peptidyl-Dipeptidase A
- Phenotype
- Polymorphism, Genetic