Detection of p53 mutations in benign and dysplastic nevi.

Article

Detection of p53 mutations in benign and dysplastic nevi.

Cancer research - 1 Oct 1995

Levin D B, Wilson K, Valadares de Amorim G, Webber J, Kenny P, Kusser W

Abstract excerpt

We have examined melanocytic cells derived directly from fresh biopsy tissue for the presence of p53 mutations. Using selective media that permits growth of melanocytes and inhibits growth of fibroblasts and keratinocytes, we established short-term, primary cultures of melanocytes from skin biops...

Topics

Base Sequence
Cells, Cultured
DNA
Dysplastic Nevus Syndrome
Exons
Genes, p53
Melanocytes
Melanoma
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

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