Initial report of a genome search for the affective disorder predisposition gene in the old order Amish pedigrees: chromosomes 1 and 11.

doi:10.1002/ajmg.1320540421

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Article

Initial report of a genome search for the affective disorder predisposition gene in the old order Amish pedigrees: chromosomes 1 and 11.

American journal of medical genetics - 15 Dec 1994

Gerhard D S, LaBuda M C, Bland S D, Allen C, Egeland J A, Pauls D L

Abstract excerpt

Family data have suggested that some forms of major affective disorder are genetic. Certain of the Old Order Amish pedigrees have a familial form of the disease. In this report we present the results of genetic analyses under autosomal dominant mode of transmission with reduced penetrance and thr...

Topics

Bipolar Disorder
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Ethnicity
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Genotype
Humans
Male
Mood Disorders
Parents
Pedigree
United States

Source

Open in PubMed

Identifiers

PMID: 7726215
DOI: 10.1002/ajmg.1320540421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7726215-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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