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Article

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.

Proceedings of the National Academy of Sciences of the United States of America - 29 Aug 1995

Yamanaka S, Balestra M E, Ferrell L D, Fan J, Arnold K S, Taylor S, Taylor J M, Innerarity T L

Abstract excerpt

Apolipoprotein (apo-) B mRNA editing is the deamination of cytidine that creates a new termination codon and produces a truncated version of apo-B (apo-B48). The cytidine deaminase catalytic subunit [apo-B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1)] of the multiprotein editing complex has been identified. We generated transgenic rabbits and mice expressing rabbit APOBEC-1 in their livers to determine...

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Identifiers

PMID: 7667315
DOI: 10.1073/pnas.92.18.8483
PMCID: PMC41181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.PMID 7667315Read ↗

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