Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Concerted integration of retrovirus-like DNA by human immunodeficiency virus type 1 integrase

1 Oct 1995

Abstract excerpt

The integration of linear retrovirus DNA by the viral integrase (IN) into the host chromosome occurs by a concerted mechanism (full-site reaction). IN purified from avian myeloblastosis virus and using retrovirus-like DNA restriction fragments (487 bp in length) as donors and circular DNA (pGEM-3) as the target can efficiently catalyze that reaction. Nonionic detergent lysates of purified human immunodeficiency...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA and Nucleic Acid Chemistry
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7666512
DOI: 10.1128/jvi.69.10.6090-6097.1995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Concerted integration of retrovirus-like DNA by human immunodeficiency virus type 1 integrasePMID 7666512Read ↗

Efficient Concerted Integration by Recombinant Human Immunodeficiency Virus Type 1 Integrase without Cellular or Viral CofactorsSemantic proximity Read ↗

The HIV-1 Integrase Monomer Induces a Specific Interaction with LTR DNA for Concerted IntegrationSemantic proximity Read ↗

Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus.Semantic proximity Read ↗

Changes in the mechanism of DNA integration in vitro induced by base substitutions in the HIV-1 U5 and U3 terminal sequences.Semantic proximity Read ↗

Molecular mechanisms of HIV integration and therapeutic interventionSemantic proximity Read ↗

Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration.Semantic proximity Read ↗

Avian retrovirus U3 and U5 DNA inverted repeats. Role Of nonsymmetrical nucleotides in promoting full-site integration by purified virion and bacterial recombinant integrases.Semantic proximity Read ↗

Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase: critical residues for concerted integration and multimerization.Semantic proximity Read ↗

Going beyond Integration: The Emerging Role of HIV-1 Integrase in Virion MorphogenesisSemantic proximity Read ↗

Retrovirus DNA termini bound by integrase communicate in trans for full-site integration in vitro.Semantic proximity Read ↗

HIV Integrase, a Brief Overview from Chemistry to TherapeuticsSemantic proximity Read ↗

Retroviral DNA Integration Directed by HIV Integration Protein in VitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.