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Article

Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1995

Silos-Santiago I, Molliver D C, Ozaki S, Smeyne R J, Fagan A M, Barbacid M, Snider W D

Abstract excerpt

Experiments over the past decade in which NGF/TrkA signaling has been abolished by antibodies or targeted gene mutations have shown that 70-85% of dorsal root ganglion (DRG) neurons require NGF for survival during development. There is consensus that many of the NGF-dependent neurons are small-diameter, peptidergic neurons subserving nociception. These neurons express the signaling receptor for NGF, TrkA. There...

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Identifiers

PMID: 7666178
PMCID: PMC6577670

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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