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Article

Neurotrophin‐3 down‐regulates trkA mRNA, NGF high‐affinity binding sites, and associated phenotype in adult DRG neurons

1 Sept 2003

Abstract excerpt

Neurotrophin-3 (NT-3) binds to multiple trks, not only its initially identified receptor trkC. Recent studies in our laboratory show that NT-3 negatively regulates nociceptive phenotype associated with the trkA subpopulation. Due to the extensive overlap in trkA and trkC expression it is uncertain whether there is a direct influence of NT-3 on trkA in adult sensory neurons. Thus, the aim of this study was to...

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Identifiers

PMID: 14511333
DOI: 10.1046/j.1460-9568.2003.02881.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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