EMG analysis of harmaline-induced tremor in normal and three strains of mutant mice with Purkinje cell degeneration and the role of the inferior olive.

doi:10.1152/jn.1995.73.6.2568

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Article

EMG analysis of harmaline-induced tremor in normal and three strains of mutant mice with Purkinje cell degeneration and the role of the inferior olive.

Journal of neurophysiology - 1 Jun 1995

Milner T E, Cadoret G, Lessard L, Smith A M

Abstract excerpt

1. The effects of intraperitoneal injections of 10 mg/kg harmaline were tested in normal mice and three strains of cerebellar mutant mice with Purkinje cell degeneration. Ten normal (wild-type) mice (+/+), as well as five lurcher (lc/+), six nervous (nr/nr), and eight Purkinje cell degeneration (...

Topics

Animals
Cerebellum
Electromyography
Harmaline
Injections, Intraperitoneal
Mice
Mice, Mutant Strains
Muscles
Mutation
Nerve Degeneration
Olivary Nucleus
Purkinje Cells
Tremor

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