Article
A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter.
Molecular and cellular biology - 1 May 1999
Mulet J M, Leube M P, Kron S J, Rios G, Fink G R, Serrano R
Abstract excerpt
The regulation of intracellular ion concentrations is a fundamental property of living cells. Although many ion transporters have been identified, the systems that modulate their activity remain largely unknown. We have characterized two partially redundant genes from Saccharomyces cerevisiae, HAL4/SAT4 and HAL5, that encode homologous protein kinases implicated in the regulation of cation uptake. Overexpression...
Topics
- Biological Transport
- Carrier Proteins
- Cation Transport Proteins
- Cations
- Cloning, Molecular
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Homeostasis
- Membrane Potentials
- Membrane Proteins
- Methylamines
- Mutation
- Phenotype