The transcriptional activator Imp2p maintains ion homeostasis in Saccharomyces cerevisiae.

doi:10.1093/genetics/149.2.893

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Article

The transcriptional activator Imp2p maintains ion homeostasis in Saccharomyces cerevisiae.

Genetics - 1 Jun 1998

Masson J Y, Ramotar D

Abstract excerpt

Yeast cells deficient in the transcriptional activator Imp2p are viable, but display marked hypersensitivity to a variety of oxidative agents. We now report that imp2 null mutants are also extremely sensitive to elevated levels of the monovalent ions, Na+ and Li+, as well as to the divalent ions Ca2+, Mn2+, Zn2+, and Cu2+, but not to Cd2+, Mg2+, Co2+, Ni2+, and Fe2+, as compared to the parent strain. We next...

Topics

Adenosine Triphosphatases
Bleomycin
Cation Transport Proteins
Cations, Divalent
Cell Cycle Proteins
Copper
Fungal Proteins
Gene Dosage
Genes, Suppressor
Homeostasis
Ion Transport
Lithium Chloride

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Multigene Family

Mutation

Nuclear Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 9611200
DOI: 10.1093/genetics/149.2.893
PMCID: PMC1460211

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