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Article

The transcriptional activator Imp2p maintains ion homeostasis in Saccharomyces cerevisiae.

Genetics - 1 Jun 1998

Masson J Y, Ramotar D

Abstract excerpt

Yeast cells deficient in the transcriptional activator Imp2p are viable, but display marked hypersensitivity to a variety of oxidative agents. We now report that imp2 null mutants are also extremely sensitive to elevated levels of the monovalent ions, Na+ and Li+, as well as to the divalent ions Ca2+, Mn2+, Zn2+, and Cu2+, but not to Cd2+, Mg2+, Co2+, Ni2+, and Fe2+, as compared to the parent strain. We next...

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PMID: 9611200
DOI: 10.1093/genetics/149.2.893
PMCID: PMC1460211

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