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Article

SRD5A2 gene mutations--a population-based review.

Pediatric endocrinology reviews : PER - 1 Sept 2010

Samtani Ratika, Bajpai Minu, Ghosh P K, Saraswathy K N

Abstract excerpt

Knowledge of steroid 5 alpha-reductase type 2 (SRD5A2) gene mutations is expanding, and its role has been implicated in various disease susceptibilities concerning reproductive health. Extensive research has revealed the tendency for specific SRD5A2 gene mutations to be passed along certain racial, ethnic and geographically isolated groups, which suggests population specificity of these mutations. The review...

Topics

3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Alleles
Dihydrotestosterone
Disorders of Sex Development
Genetic Variation
Genitalia, Male
Humans
Hypospadias
Male
Membrane Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Population Groups

Prostatic Neoplasms

Testosterone

Source

Identifiers

PMID: 21037542

Provenance

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