Genetic variation of 3 beta-hydroxysteroid dehydrogenase type II in three racial/ethnic groups: implications for prostate cancer risk.

doi:10.1002/(sici)1097-0045(19970915)33:1<9::aid-pros2>3.0.co;2-h

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Article

Genetic variation of 3 beta-hydroxysteroid dehydrogenase type II in three racial/ethnic groups: implications for prostate cancer risk.

The Prostate - 15 Sept 1997

Devgan S A, Henderson B E, Yu M C, Shi C Y, Pike M C, Ross R K, Reichardt J K

Abstract excerpt

BACKGROUND: Elevated prostatic dihydrotestosterone (DHT) has been suggested to increase the risk of prostate cancer. The HSD3B2 gene encodes the type II 3 beta-hydroxysteroid dehydrogenase: one of two enzymes that initiate the inactivation of DHT. Thus, the HSD3B2 gene is a candidate gene for pre...

Topics

3-Hydroxysteroid Dehydrogenases
Alleles
Asian People
Black People
Dinucleotide Repeats
Genetic Predisposition to Disease
Genetic Variation
Humans
Isoenzymes
Male
Polymorphism, Genetic
Prostatic Neoplasms
Racial Groups
Risk Factors
White People
Black or African American

Source

Open in PubMed

Identifiers

PMID: 9294620
DOI: 10.1002/(sici)1097-0045(19970915)33:1<9::aid-pros2>3.0.co;2-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9294620-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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