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Article

Enhanced PCR amplification of VNTR locus D1S80 using peptide nucleic acid (PNA).

Nucleic acids research - 11 Aug 1995

Demers D B, Curry E T, Egholm M, Sozer A C

Abstract excerpt

Use of the polymerase chain reaction (PCR) to amplify variable numbers of tandem repeat (VNTR) loci has become widely used in genetic typing. Unfortunately, preferential amplification of small allelic products relative to large allelic products may result in incorrect or ambiguous typing in a het...

Topics

Base Sequence
DNA
DNA Primers
Genetic Carrier Screening
Genotype
Humans
Minisatellite Repeats
Molecular Sequence Data
Nucleic Acid Renaturation
Oligonucleotides, Antisense
Peptides
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7659530
DOI: 10.1093/nar/23.15.3050
PMCID: PMC307148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7659530-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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