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Article

Inactivation of the CDKN2A and the p53 tumour suppressor genes in external genital carcinomas and their precursors

28 Nov 2006

Abstract excerpt

BACKGROUND: p53 has been extensively studied in external genital carcinoma (EGC), and is frequently inactivated, but little is known about the role of the CDKN2A tumour suppressor gene in the oncogenesis of EGC. OBJECTIVES: To investigate the role of CDKN2A and p53 in the pathogenesis of EGCs and their precursor lesions vulval intraepithelial neoplasia (VIN3), penile intraepithelial neoplasia and lichen sclerosus...

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Identifiers

PMID: 17300232
DOI: 10.1111/j.1365-2133.2006.07604.x

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