A mutation that decreases the efficiency of plasmid R1 replication leads to the activation of parD, a killer stability system of the plasmid.

doi:10.1111/j.1574-6968.1995.tb07709.x

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Article

A mutation that decreases the efficiency of plasmid R1 replication leads to the activation of parD, a killer stability system of the plasmid.

FEMS microbiology letters - 1 Aug 1995

Ruiz-Echevarría M J, de la Torre M A, Díaz-Orejas R

Abstract excerpt

The silent parD (kis/kid) stability operon of plasmid R1 is normally repressed by the co-ordinated action of the Kis and Kid proteins. In this report it is shown that a mutation in repA, the gene of the plasmid replication protein, that reduces two-fold the copy number of the plasmid, leads to th...

Topics

Bacterial Proteins
Base Sequence
DNA Helicases
DNA-Binding Proteins
Molecular Sequence Data
Mutation
Plasmids
Proteins
Trans-Activators
Transcription, Genetic

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