Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural and functional comparison between the stability systems ParD of plasmid R1 and Ccd of plasmid F.

Molecular & general genetics : MGG - 1 Mar 1991

Ruiz-Echevarría M J, de Torrontegui G, Giménez-Gallego G, Díaz-Orejas R

Abstract excerpt

The stability determined by the systems ParD of plasmid R1 and Ccd of plasmid F is due to the concerted action of two proteins, a cytotoxin and an antagonist of this function. In this paper we report that CcdA and Kis proteins, the antagonists of the Ccd and ParD systems respectively, share significant sequence homologies at both ends. In Kis, these regions seem to correspond to two different domains. Despite the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Escherichia coli

Share to Genotype

Share to Kinetics

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 2017133
DOI: 10.1007/BF00261674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural and functional comparison between the stability systems ParD of plasmid R1 and Ccd of plasmid F.PMID 2017133Read ↗

Genetic identification of two functional regions in the antitoxin of the parD killer system of plasmid R1.Semantic proximity Read ↗

Identification of residues of the kid toxin involved in autoregulation of the parD system.Semantic proximity Read ↗

A mutation that decreases the efficiency of plasmid R1 replication leads to the activation of parD, a killer stability system of the plasmid.Semantic proximity Read ↗

F plasmid CcdB killer protein: ccdB gene mutants coding for non-cytotoxic proteins which retain their regulatory functions.Semantic proximity Read ↗

Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin.Semantic proximity Read ↗

Kis antitoxin couples plasmid R1 replication and parD (kis,kid) maintenance modules.Semantic proximity Read ↗

Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2.Semantic proximity Read ↗

Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes.Semantic proximity Read ↗

Probing the N-terminus of ParB using cysteine-scanning mutagenesis and thiol modification.Semantic proximity Read ↗

The ratio between CcdA and CcdB modulates the transcriptional repression of the ccd poison-antidote system.Semantic proximity Read ↗

Mechanism of DNA segregation in prokaryotes: ParM partitioning protein of plasmid R1 co-localizes with its replicon during the cell cycle.Semantic proximity Read ↗

Expression of the F plasmid ccd toxin-antitoxin system in Escherichia coli cells under nutritional stress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.