Article
Structure of rotavirus particle: interaction of the inner capsid protein VP6 with the core polypeptide VP3.
Biological research - 1 Jan 1994
Sandino A M, Fernandez J, Pizarro J, Vasquez M, Spencer E
Abstract excerpt
The structural relationship between VP6 (inner capsid polypeptide) and the viral core was studied using chemical cross-linking with dithiobis(succinimidyl propionate). Crosslinked single shelled and reconstituted rotavirus particles, suggest the existence of a complex organization of VP6 molecules in the inner capsid and a direct interaction with the core polypeptide VP3. The inhibition of the recovery of RNA...
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