Article
Changes in the hepatitis B virus precore and core regions in association with the disappearance of hepatitis B e antigen in patients with chronic hepatitis B.
Internal medicine (Tokyo, Japan) - 1 May 1995
Nakayama J, Nakanishi T, Arataki K, Obatake T, Moriya T, Kajiyama G
Abstract excerpt
Disappearance of the hepatitis B e antigen (HBeAg) typically signals the remission of chronic hepatitis B; however, HBeAg defective variants have been identified in patients with HBeAg negative chronic hepatitis (CH). We studied the changes in the hepatitis B virus (HBV) genome associated with HB...
Topics
- Adult
- Base Sequence
- Chronic Disease
- Female
- Gene Deletion
- Genome, Viral
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Molecular Sequence Data
- Mutation