Article
Isolation of Xenopus LMP-7 homologues. Striking allelic diversity and linkage to MHC.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1995
Namikawa C, Salter-Cid L, Flajnik M F, Kato Y, Nonaka M, Sasaki M
Abstract excerpt
The mammalian low molecular mass protein-7 (LMP-7) gene resides in the class II region of the MHC, and its product is most probably involved, as a component of a proteasome, in the processing of Ags to be presented by the MHC class I molecules. To elucidate the evolution of the LMP-7 gene at both...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Southern
- Cysteine Endopeptidases
- DNA, Complementary
- Genetic Linkage
- Humans
- Major Histocompatibility Complex
- Mice