Article
mRNAs for insulin-like growth factor-II (IGF-II) and variant IGF-II are co-expressed in human fetal ovary and uterus.
Molecular and cellular endocrinology - 1 Sept 1991
Yeh J, Danehy F T, Osathanondh R, Villa-Komaroff L
Abstract excerpt
Insulin-like growth factor-II (IGF-II) is postulated to have autocrine and/or paracrine functions in developing fetal tissues, but has never been reported in human fetal reproductive organs. The forms of IGF-II found in normal human serum include a 67 amino acid form and a variant form resulting from alternate splicing of the mRNA such that Ser-29 is replaced by four other amino acid residues. We studied the...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA
- Female
- Genetic Variation
- Humans
- Insulin-Like Growth Factor II
- Molecular Sequence Data
- Ovary
- Polymerase Chain Reaction