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Article

Identification of Ser-1275 and Ser-1309 as autophosphorylation sites of the insulin receptor.

FEBS letters - 2 Jan 1997

Al-Hasani H, Eisermann B, Tennagels N, Magg C, Passlack W, Koenen M, Müller-Wieland D, Meyer H E, Klein H W

Abstract excerpt

We have identified Ser-1275 and Ser-1309 as novel serine autophosphorylation sites by direct sequencing of HPLC-purified tryptic phosphopeptides of the histidine-tagged insulin receptor kinase IRKD-HIS. The corresponding peptides (Ser-1275, amino acids 1272-1292; Ser-1309, amino acids 1305-1313) have been detected in the HPLC profiles of both the soluble kinase IRKD, which contains the entire cytoplasmic domain...

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Source

Identifiers

PMID: 9000514
DOI: 10.1016/s0014-5793(96)01342-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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