Article
Soluble insulin-like growth factor II/mannose 6-phosphate receptor carries multiple high molecular weight forms of insulin-like growth factor II in fetal bovine serum.
The Journal of biological chemistry - 7 Jul 1995
Valenzano K J, Remmler J, Lobel P
Abstract excerpt
We have characterized a soluble form of the insulin-like growth factor II/mannose 6-phosphate receptor (sIGF-II/MPR) and bound ligands from bovine serum. Fetal serum contained 2-8 mg/liter sIGF-II/MPR. Affinity-purified receptor isolated by adsorption to phosphomannan-agarose and elution with man...
Topics
- Animals
- Biological Transport
- Blood Proteins
- Body Fluids
- Cattle
- Chromatography, Affinity
- Cross Reactions
- Fetal Blood
- Genetic Variation
- Glycosylation
- Insulin-Like Growth Factor II
- Ligands
- Molecular Weight
- Protein Processing, Post-Translational
- Receptor, IGF Type 2
- Sequence Analysis
- Solubility