Article
Insulin-like growth factor II (IGF-II).
The international journal of biochemistry & cell biology - 1 Jul 1998
O'Dell S D, Day I N
Abstract excerpt
Insulin-like growth factor II (IGF-II) plays a key role in mammalian growth, influencing foetal cell division and differentiation and possibly metabolic regulation. The mature 67 amino acid peptide shares sequence homology with both insulin and IGF-I. The liver is the main endocrine source of IGFs, but autocrine/paracrine activity is found in most tissues. The type 1 receptor mediates most of the biological...
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