Article
Distinct changes in HIV type 1 RNA versus p24 antigen levels in serum during short-term zidovudine therapy in asymptomatic individuals with and without progression to AIDS.
AIDS research and human retroviruses - 1 Apr 1995
Jurriaans S, Weverling G J, Goudsmit J, Boogaard J, Brok M, Van Strijp D, Lange J, Koot M, Van Gemen B
Abstract excerpt
Serum HIV-1 RNA and p24 antigen levels were examined in 28 seropositive asymptomatic individuals participating in a trial on the efficacy of zidovudine. Sixteen individuals remained asymptomatic until 4 years after the onset of the trial, whereas 12 individuals were diagnosed with an AIDS-defining event. The serum HIV-1 RNA load and p24 antigen levels were determined before the onset of therapy and during the...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Base Sequence
- DNA Primers
- DNA, Viral
- Double-Blind Method
- HIV Core Protein p24
- HIV Infections
- HIV-1
- Humans