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Article

Structural and functional roles of cysteine 90 and cysteine 240 in S-adenosylmethionine synthetase.

The Journal of biological chemistry - 4 Aug 1995

Reczkowski R S, Markham G D

Abstract excerpt

Site-specific mutagenesis was performed on the structural gene for Escherichia coli S-adenosylmethionine (AdoMet) synthetase to introduce mutations at cysteines 90 and 240, residues previously implicated by chemical modification studies to be catalytically and/or structurally important. The AdoMet synthetase mutants (i.e. MetK/C90A, MetK/C90S, and MetK/C240A) retained up to approximately 10% of wild type...

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Identifiers

PMID: 7629176
DOI: 10.1074/jbc.270.31.18484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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