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Article

Characterization of the S289A,D mutants of yeast cystathionine beta-synthase.

Biochimica et biophysica acta - 1 Jun 2009

Quazi Faraz, Aitken Susan M

Abstract excerpt

Cystathionine beta-synthase (CBS) catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of l-serine and l-homocysteine to form l-cystathionine in the first step of the reverse transsulfuration pathway. Residue S289 of yeast CBS, predicted to form a hydrogen bond with the pyridine nitr...

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Source

Identifiers

PMID: 19264153
DOI: 10.1016/j.bbapap.2009.02.007

Genes

CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19264153-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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