Article
Functional interactions between posttranslationally modified amino acids of methyl-coenzyme M reductase in Methanosarcina acetivorans.
PLoS biology - 1 Feb 2020
Nayak Dipti D, Liu Andi, Agrawal Neha, Rodriguez-Carerro Roy, Dong Shi-Hui, Mitchell Douglas A, Nair Satish K, Metcalf William W
Abstract excerpt
The enzyme methyl-coenzyme M reductase (MCR) plays an important role in mediating global levels of methane by catalyzing a reversible reaction that leads to the production or consumption of this potent greenhouse gas in methanogenic and methanotrophic archaea. In methanogenic archaea, the alpha subunit of MCR (McrA) typically contains four to six posttranslationally modified amino acids near the active site....
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