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Article

Deconstruction of the catalytic array within the amidotransferase subunit of carbamoyl phosphate synthetase.

Biochemistry - 30 Nov 1999

Huang X, Raushel F M

Abstract excerpt

Carbamoyl phosphate synthetase from Escherichia coli catalyzes the formation of carbamoyl phosphate from bicarbonate, glutamine, and two molecules of ATP. The enzyme consists of a large synthetase subunit, and a small amidotransferase subunit, which belongs to the Triad family of glutamine amidotransferases. Previous studies have established that the reaction mechanism of the small subunit proceeds through the...

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Identifiers

PMID: 10625457
DOI: 10.1021/bi991805q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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