Article
Inhibition of an Erythroid Differentiation Switch by the Helix-Loop-Helix Protein Id1
1 Jul 1995
Abstract excerpt
The Id proteins function as negative regulators of basic-helix-loop-helix transcription factors, which play important roles in determination of cell lineage and in tissue-specific differentiation. Down-regulation of Id1 mRNA is associated with dimethyl sulfoxide-induced terminal differentiation of mouse erythroleukemia cells. To examine the significance of Id1 down-regulation in erythroid differentiation, we...
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