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Article

Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin.

The Journal of biological chemistry - 28 Jul 1995

Yamauchi K, Ribon V, Saltiel A R, Pessin J E

Abstract excerpt

Immunoprecipitation of the cytosolic Src homology 2 domain-containing protein-tyrosine phosphatase, SHPTP2, from insulin-stimulated 3T3L1 adipocytes or Chinese hamster ovary cells expressing the human insulin receptor resulted in the coimmunoprecipitation of a diffuse tyrosine-phosphorylated band in the 115-kDa protein region on SDS-polyacrylamide gels. Although platelet-derived growth factor induced the tyrosine...

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PMID: 7629070
DOI: 10.1074/jbc.270.30.17716

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Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin.PMID 7629070Read ↗

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