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Article

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

28 Jul 1995

Abstract excerpt

The gene product of the ob locus is important in the regulation of body weight. The ob product was shown to be present as a 16-kilodalton protein in mouse and human plasma but was undetectable in plasma from C57BL/6J ob/ob mice. Plasma levels of this protein were increased in diabetic (db) mice, a mutant thought to be resistant to the effects of ob. Daily intraperitoneal injections of either mouse or human...

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Identifiers

PMID: 7624777
DOI: 10.1126/science.7624777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> GenePMID 7624777Read ↗

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