Article
A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver.
Molecular and cellular biology - 1 Aug 1995
Sueyoshi T, Kobayashi R, Nishio K, Aida K, Moore R, Wada T, Handa H, Negishi M
Abstract excerpt
Expression of the Cyp 2d-9 (steroid 16 alpha-hydroxylase) gene in mouse liver is male specific in such Mus musculus domesticus strains as FVB/N, whereas the corresponding P450 genes in the wild mouse species Mus spretus are not sex specific in their expression. These parental differences in the gene expressions were independently inherited in F1 offspring from crosses of FVB/N and M. spretus. A 5' flanking...
Topics
- Amino Acid Sequence
- Animals
- Aryl Hydrocarbon Hydroxylases
- Base Sequence
- Cell Nucleus
- Cloning, Molecular
- Crosses, Genetic
- Cytochrome P-450 Enzyme System
- DNA-Binding Proteins
- Escherichia coli
- Gene Expression Regulation, Enzymologic
