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Article

Regulation of mouse Ah receptor (Ahr) gene basal expression by members of the Sp family of transcription factors.

DNA and cell biology - 1 Sept 1998

Fitzgerald C T, Nebert D W, Puga A

Abstract excerpt

The aromatic hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates the expression of several drug-metabolizing enzymes and has been implicated in immunosuppression, teratogenesis, cell-specific hyperplasia, and certain types of malignancies and toxicities. The mouse Ahr gene 5' proximal promoter region, which contains four potential Sp1 motifs, is required for efficient basal...

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Source

Identifiers

PMID: 9778040
DOI: 10.1089/dna.1998.17.811

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Regulation of mouse Ah receptor (Ahr) gene basal expression by members of the Sp family of transcription factors.PMID 9778040Read ↗

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