Article
Stability of wild-type and temperature-sensitive protein subunits of the phage P22 capsid.
The Journal of biological chemistry - 14 Jul 1995
Galisteo M L, Gordon C L, King J
Abstract excerpt
Temperature-sensitive folding (tsf) mutants of the phage P22 coat protein prevent newly synthesized polypeptide chains from reaching the conformation competent for capsid assembly in cells, and can be rescued by the GroEL chaperone (Gordon, C., Sather, S., Casjens, S., and King, J. (1994) J. Biol. Chem. 269, 27941-27951). Here we investigate the stabilities of wild-type and four tsf mutant unpolymerized subunits....
Topics
- Bacteriophage P22
- Capsid
- Mutation
- Protein Conformation
- Protein Denaturation
- Protein Folding
- Temperature