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Article

GroEL binds a late folding intermediate of phage P22 coat protein.

Cell stress & chaperones - 1 Jul 2000

de Beus M D, Doyle S M, Teschke C M

Abstract excerpt

GroEL recognizes proteins that are folding improperly or that have aggregation-prone intermediates. Here we have used as substrates for GroEL, wildtype (WT) coat protein of phage P22 and 3 coat proteins that carry single amino acid substitutions leading to a temperature-sensitive folding (tsf) phenotype. In vivo, WT coat protein does not require GroEL for proper folding, whereas GroEL is necessary for the folding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11005374
DOI: 10.1379/1466-1268(2000)005<0163:gbalfi>2.0.co;2
PMCID: PMC312882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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