Article
Histone H4 and the maintenance of genome integrity.
Genes & development - 15 Jul 1995
Megee P C, Morgan B A, Smith M M
Abstract excerpt
The normal progression of Saccharomyces cerevisiae through nuclear division requires the function of the amino-terminal domain of histone H4. Mutations that delete the domain, or alter 4 conserved lysine residues within the domain, cause a marked delay during the G2+M phases of the cell cycle. Si...
Topics
- Amino Acid Sequence
- Arginine
- Conserved Sequence
- DNA Damage
- G2 Phase
- Gene Expression Regulation, Fungal
- Genome, Fungal
- Histones
- Lysine
- Mitosis
- Molecular Sequence Data
- Mutagenesis, Insertional
- Mutation