Article
Histone H4 and the maintenance of genome integrity.
Genes & development - 15 Jul 1995
Megee P C, Morgan B A, Smith M M
Abstract excerpt
The normal progression of Saccharomyces cerevisiae through nuclear division requires the function of the amino-terminal domain of histone H4. Mutations that delete the domain, or alter 4 conserved lysine residues within the domain, cause a marked delay during the G2+M phases of the cell cycle. Site-directed mutagenesis of single and multiple lysine residues failed to map this phenotype to any particular site; the...
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